Iria - Zeiram the Animation

Beginning with her older brother Gren, a seasoned bounty hunter, and his companion Bob, who work for Ghomvak Security along with a slightly loutish hunter named Fujikuro, the novel introduces Iria as an apprentice. During a rescue mission to the Karma, a spaceship that has been taken over, they learn that the hijacker is actually Zeiram, an alien that appears to be invincible and who started killing the crew while the ship was in journey. Zeiram seriously injures Bob while he rescues the survivors, and Gren gets separated from the group while attempting to kill Zeiram by destroying the Karma. When Iria returns to Myce, she finds herself the target of assassins working for Tedan Tippedai, the company that possessed the Karma, and learns of a covert plan to manipulate Zeiram so that it can be used as a weapon. With the aid of Fujikuro, Iria manages to flee and meets up with Bob, who never fully recovered from his wounds despite having his mind downloaded into a computer program. Together, they continue to look into reports that Zeiram has visited Myce, as well as try to learn what happened to Gren, who also appears to have survived the destruction of the Karma.